Their effects are often difficult to relate to the presence of heavy metals, since their polluting power is cumulative, not immediate and does not affect all people equally.
In general, they can cause the most diverse symptoms of disease: liver and kidney damage, nerve disorders, infections, allergies, anemia, bone deformities and cancer. They are not degraded in the body, but are deposited and accumulated in the kidneys, for example, bones or skin (especially in the subcutaneous fat skin layer).
Each metal also has its peculiarities, for example, lead impairs reproductive capacity: it decreases sperm and increases premature births and abortions. Fortunately, external levels have decreased with the advent of unleaded gasoline.